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大鼠发情周期中子宫内的糖苷酶

Glycosidases in the rat uterus during the oestrus cycle.

作者信息

Pizarro R A, de Courel H R, de Giraudo R H, de Martínez N R

出版信息

Acta Physiol Pharmacol Latinoam. 1984;34(3):271-6.

PMID:6099686
Abstract

Seven acid glycosidases activities have been measured in normal rat uterus during the oestrus cycle. It has been observed that alpha-fucosidase, alpha-mannosidase, beta-galactosidase, alpha-galactosidase, aryl sulfatase, acid phosphatase and hexosaminidase activities changed cyclically during the oestrus cycle. From onward oestrus to metaoestrus the enzyme activities are in their highest level, but then decline slightly towards the resting one, as the cycle progresses. It is possible that changes in glycosidases content bear a lysosomal relationship, since it is known the increase in the lysosome content of the uterus during the oestrus and metaoestrus. The increased enzyme content could be related to uterus glycoproteins secretion and degradation during the normal oestrus cycle.

摘要

在发情周期中测定了正常大鼠子宫中七种酸性糖苷酶的活性。据观察,α-岩藻糖苷酶、α-甘露糖苷酶、β-半乳糖苷酶、α-半乳糖苷酶、芳基硫酸酯酶、酸性磷酸酶和己糖胺酶的活性在发情周期中呈周期性变化。从发情期开始到间情期,酶活性处于最高水平,但随着周期的推进,随后会向静止期略有下降。糖苷酶含量的变化可能与溶酶体有关,因为已知发情期和间情期子宫中溶酶体含量会增加。酶含量的增加可能与正常发情周期中子宫糖蛋白的分泌和降解有关。

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