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1
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Br J Clin Pharmacol. 1984;18 Suppl 2(Suppl 2):243S-247S. doi: 10.1111/j.1365-2125.1984.tb02603.x.
2
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J Cardiovasc Pharmacol. 1985;7 Suppl 1:S45-51. doi: 10.1097/00005344-198507001-00010.
4
Brachial artery hemodynamic response to acute converting enzyme inhibition by enalaprilat in essential hypertension.依那普利拉对原发性高血压患者肱动脉血流动力学的急性转换酶抑制作用。
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Estimation of forearm arterial compliance in normal and hypertensive men from simultaneous pressure and flow measurements in the brachial artery, using a pulsed Doppler device and a first-order arterial model during diastole.在舒张期，使用脉冲多普勒装置和一阶动脉模型，通过同时测量肱动脉的压力和血流来估计正常男性和高血压男性的前臂动脉顺应性。
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Post-synaptic alpha-blockade and brachial artery compliance in essential hypertension.原发性高血压中突触后α受体阻滞与肱动脉顺应性
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Pulsed Doppler: determination of diameter, blood flow velocity, and volumic flow of brachial artery in man.脉冲多普勒：测定人体肱动脉的直径、血流速度和容积流量。
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Comparison of oral MK 421 and propranolol in mild to moderate essential hypertension and their effects on arterial and venous vessels of the forearm.口服MK 421与普萘洛尔治疗轻至中度原发性高血压的比较及其对前臂动静脉血管的影响。
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高血压患者中的血管紧张素转换酶抑制与肱动脉血流动力学

ACE inhibition and brachial artery haemodynamics in hypertension.

作者信息

Simon A C, Levenson J A, Safar A M, Bouthier J D, Safar M E

出版信息

Br J Clin Pharmacol. 1984;18 Suppl 2(Suppl 2):243S-247S. doi: 10.1111/j.1365-2125.1984.tb02603.x.

DOI:10.1111/j.1365-2125.1984.tb02603.x
PMID:6099739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1463472/
Abstract

Brachial artery haemodynamics, including arterial diameter, blood flow velocity, blood flow and compliance of the brachial artery may be evaluated non-invasively in man, using pulsed Doppler methods. In patients with sustained untreated essential hypertension, brachial artery diameter is increased, blood flow is normal and arterial compliance is reduced independently of the level of blood pressure. Converting enzyme inhibition may reverse the large artery abnormalities, causing an increase in arterial diameter, blood flow and arterial compliance both in acute and long-term investigations. These changes in large arteries may contribute towards improved cardiovascular morbidity and less mortality in treated hypertensive patients.

摘要

利用脉冲多普勒方法，可以对人体肱动脉血流动力学进行无创评估，包括动脉直径、血流速度、血流量以及肱动脉的顺应性。在未经治疗的持续性原发性高血压患者中，肱动脉直径增大，血流量正常，动脉顺应性降低，且与血压水平无关。在急性和长期研究中，转换酶抑制可逆转大动脉异常，使动脉直径、血流量和动脉顺应性增加。大动脉的这些变化可能有助于改善接受治疗的高血压患者的心血管发病率并降低死亡率。