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[先天性脑积水:临床病理表现]

[Congenital hydrocephalus: clinico-pathological picture].

作者信息

Della Giustina E, Pace P, Lugli N, Botticelli A R

出版信息

Pediatr Med Chir. 1982 Nov-Dec;4(6):607-20.

PMID:6100512
Abstract

The authors review the main pathologic causes of congenital hydrocephalus from ischemic-vascular injuries, embryofoetal infections and dysraphisms to genetic ones. Abundant illustrations of each condition are furnished and particular attention is paid to each situation, discussing the available pathogenetic mechanisms and hypothesis. Genetic "sine causa" hydrocephalus and X-linked hydrocephalus are mainly stressed, presenting some personal data. The clinic aspects of the varying forms of hydrocephalus are continuously kept in mind and a terminal paragraph details the clinical and neuroradiological means determinant in differential diagnosis versus similar conditions such as hydranencephaly, porencephaly, aracnoid cysts, holoprosencephaly and agenesis of corpus callosum.

摘要

作者回顾了先天性脑积水的主要病理原因,从缺血性血管损伤、胚胎胎儿感染、脊柱裂到遗传因素。文中提供了每种情况的大量插图,并对每种情况给予特别关注,讨论了现有的发病机制和假说。重点强调了遗传性“无明确病因”脑积水和X连锁脑积水,并展示了一些个人数据。文中始终关注不同形式脑积水的临床方面,最后一段详细介绍了在与诸如积水性无脑畸形、脑穿通畸形、蛛网膜囊肿、前脑无裂畸形和胼胝体发育不全等相似病症进行鉴别诊断时起决定性作用的临床和神经放射学方法。

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