Chouza C, Navarro A, Purriel J A, Pou G, de Tenyi A, Wozniak A, Touyá J
Instituto de Neurología, Montevideo, Uruguay.
Acta Neurol Latinoam. 1981;27(3-4):155-66.
The authors present an exceptional case of chemodectoma jugulare with important invasion of the skull base involving all the cranial nerves on one side and conforming Garcin's syndrome. Practically all the possible ways of spreading were followed by the tumor, with involvement of the posterior, middle and anterior fossas of the skull base and also orbit, middle ear and neck. The clinical and histopathological difficulties in the diagnosis, especially when the chemodectoma has only neurological signs, are stressed. The association of otologic symptoms makes the diagnosis easier. The patient had an early onset of the symptoms and a rapid evolution considering this type of tumors. The appearance of goitre in this patient is a sign of endocrine disturbance, which is occasionally associated with these tumors. Apparently this chemodectoma was not a secreting tumor, since the blood pressure values were normal. No signs of multicentricity or metastatic growths were detected. The radiological studies, and especially computerized tomography scanning, gave precise information about the spreading of the tumor. The authors consider that the knowledge of this entity is important in order to arrive at a correct diagnosis.
作者报告了一例罕见的颈静脉球瘤病例,该肿瘤严重侵犯颅底,累及一侧所有颅神经,符合加欣综合征。实际上,肿瘤采用了几乎所有可能的扩散途径,累及颅底后颅窝、中颅窝和前颅窝,以及眼眶、中耳和颈部。文中强调了诊断过程中临床和组织病理学方面的困难,尤其是当颈静脉球瘤仅有神经症状时。耳科症状的出现使诊断更容易。考虑到这类肿瘤,该患者症状出现早且进展迅速。该患者出现甲状腺肿是内分泌紊乱的迹象,这种情况偶尔与这些肿瘤相关。显然,这个颈静脉球瘤不是分泌性肿瘤,因为血压值正常。未检测到多中心性或转移性生长的迹象。放射学检查,尤其是计算机断层扫描,提供了有关肿瘤扩散的精确信息。作者认为,了解这一实体对于做出正确诊断很重要。