通过脂质体包裹的凝血因子 VIII 在胃肠道的吸收对甲型血友病进行口服治疗。
Oral treatment of haemophilia A by gastrointestinal absorption of factor VIII entrapped in liposomes.
作者信息
Hemker H C, Hermens W T, Muller A D, Zwaal R F
出版信息
Lancet. 1980 Jan 12;1(8159):70-1. doi: 10.1016/s0140-6736(80)90495-x.
PMID:6101418
Abstract
Factor-VIII-loaded liposomes were given orally to a patient with severe haemophilia A. Plasma concentrations of factor VIII rose to therapeutically effective levels, that persisted for 50 hours.
摘要
将负载凝血因子VIII的脂质体口服给予一名重度甲型血友病患者。血浆中凝血因子VIII的浓度升至治疗有效水平，并持续了50小时。
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