Caroff S N
J Clin Psychiatry. 1980 Mar;41(3):79-83.
The neuroleptic malignant syndrome (NMS) is an evidently underdiagnosed but potentially lethal consequence of treatment with potent neuroleptics. The author presents a detailed review of the clinical characteristics and differential diagnosis of the NMS as described in the world literature. Further studies of the incidence, etiology and pathogenesis of the NMS may enhance knowledge of neuroleptic pharmacology and produce more effective means of prevention and treatment.
抗精神病药恶性综合征（NMS）显然是一种诊断不足但使用强效抗精神病药治疗时可能致命的后果。作者对世界文献中描述的NMS的临床特征和鉴别诊断进行了详细综述。对NMS的发病率、病因和发病机制的进一步研究可能会增进对抗精神病药药理学的了解，并产生更有效的预防和治疗方法。
