The influence of adenosine 3',5'-monophosphate upon the activity of the membrane-associated (Ca+ + Mg2+)-dependent adenosine triphosphatase of the human erythrocyte.

The phosphohydrolase activity of the membrane-associated (Ca2+ + Mg2+)-dependent adenosine triphosphatase (ATPase) of the human erythrocyte can be inhibited by micromolar of nanomolar concentrations of cyclic AMP. Millimolar concentrations of cyclic AMP are less effective. The inhibitory effect of cyclic AMP is potentiated in the presence of the phosphodiesterase inhibitor, theophylline.