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[腐胺与包括纤连蛋白在内的血浆蛋白特异性结合的免疫化学证据]

[Immunochemical evidence for the specific binding of putrescine to plasma proteins including fibronectin].

作者信息

Roch A M, Quash G, Huppert J

出版信息

C R Seances Acad Sci D. 1980 Feb 11;290(6):449-52.

PMID:6102496
Abstract

Human plasma contains proteins capable of binding 14C putrescine by the action of Ca++ activated transglutaminase. These proteins have molecular weights from 32 to 220 K and above. One of these (with a molecular weight of 220 K) has been identified as fibronectin by the use of an antifibronectin antiserum. Evidence for a protein with a molecular weight identical to that of fibronectin has been obtained on PAGE analysis of the precipitate formed on incubating human serum with antipolyamine antiserum.

摘要

人血浆含有能够通过Ca++激活的转谷氨酰胺酶的作用结合14C腐胺的蛋白质。这些蛋白质的分子量在32至220K及以上。其中一种(分子量为220K)已通过使用抗纤连蛋白抗血清鉴定为纤连蛋白。在用抗多胺抗血清孵育人血清形成的沉淀物的PAGE分析中,已获得分子量与纤连蛋白相同的蛋白质的证据。

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