放射变应原吸附试验用于腔肠动物毒素特异性免疫球蛋白E研究。

Use of the radioallergosorbent test for the study of coelenterate toxin-specific immunoglobulin E.

作者信息

Hartman K R, Calton G J, Burnett J W

出版信息

Int Arch Allergy Appl Immunol. 1980;61(4):389-93. doi: 10.1159/000232466.

Abstract

The radioallergosorbent test (RAST) was adapted for use to screen the immune response to sea nettle (Chrysaora quinquecirrha) and Protuguese man-o'-war (Physalia physalis) toxins. The results of a preliminary screening of serum from patients varying in their reaction to envenomations indicate the potential of these toxin proteins to induce an allergic state in humans and illustrate the use of the RAST as a screening device to detect persons sensitive to coelenterate stings.

摘要

放射变应原吸附试验（RAST）被改编用于筛查对海荨麻（Chrysaora quinquecirrha）和僧帽水母（Physalia physalis）毒素的免疫反应。对毒液反应各异的患者血清进行初步筛查的结果表明，这些毒素蛋白有在人类中诱发过敏状态的可能性，并说明了使用RAST作为一种筛查手段来检测对腔肠动物蜇伤敏感的人。