Zefirov A L, Poletaev G I, Gusel'nikova G G
Biofizika. 1980 Jan-Feb;25(1):115-9.
It has been shown on neuro-muscular preparations of frog sartorius muscle that chromium ions in the concentrations 1-4 x 10(-6) g/ml strengthen spontaneous and evoked transmitter release. Cr3+ ions in the concentrations above 4 x 10(-6) g/ml decrease the membrane potential of muscle fibres, decrease the quantum content of the end plate potentials. Experiments on a single Ranvier node have shown that Cr3+ ions decrease the amplitude, increase the rate and duration of the action potential of a nerve fibre. It is concluded that chromium ions produce a pronounced effect on synaptic transmission, which differs significantly from the action of manganese, cobalt and nickel ions.
在青蛙缝匠肌的神经肌肉标本上已表明,浓度为1 - 4×10⁻⁶克/毫升的铬离子可增强自发和诱发的递质释放。浓度高于4×10⁻⁶克/毫升的Cr³⁺离子会降低肌纤维的膜电位,减少终板电位的量子含量。在单个郎飞结上进行的实验表明,Cr³⁺离子会降低神经纤维动作电位的幅度,增加其速率和持续时间。得出的结论是,铬离子对突触传递有显著影响,这与锰、钴和镍离子的作用有很大不同。