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[使用氟硝西泮治疗精神病患者的经验]

[Experience in using fenazepam to treat psychotic patients].

作者信息

Nuller Iu L, Tochilov V A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(6):914-20.

PMID:6106340
Abstract

Fenazepam, a potent anxiolytic tranquillizer (7-brom-5/o-chlorphenyl/1,2-dihydro-3H-1,4-benzodiazepin-2-on) was used in the treatment of 173 psychotic patients ( schizophrenia, endogenous depressions, involutional and organic psychoses). In all cases the clinical picture was characterized by anxiety. In 37% of the patients the psychopathological symptomatology disappeared altogether, in 27% there was a significant improvement. The best results were attained in the treatment of anxious-depressive, depersonalization and affective-delusional states. Anxious-depressive conditions in endogenous depressions gave worse results during fenazepam treatment, than in schizophrenia and organic brain disorders. Affective-delusional attacks were arrested by fenazepam in the initial phases. A good effect was also seen in depersonalization.

摘要

非那西泮是一种强效抗焦虑镇静剂(7-溴-5/邻氯苯基/1,2-二氢-3H-1,4-苯并二氮杂卓-2-酮),用于治疗173例精神病患者(精神分裂症、内源性抑郁症、更年期和器质性精神病)。所有病例的临床表现均以焦虑为特征。37%的患者精神病理症状完全消失,27%的患者有显著改善。在治疗焦虑抑郁、人格解体和情感妄想状态方面取得了最佳效果。在内源性抑郁症中,焦虑抑郁状态在非那西泮治疗期间的效果比精神分裂症和器质性脑疾病更差。情感妄想发作在初期被非那西泮阻止。在人格解体方面也观察到了良好效果。

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