Andersson K E
Postgrad Med J. 1980;56 Suppl 2:7-16.
The interaction between drug and receptor evokes a series of reactions resulting in a physiological response. A recognition site, an amplifier system and an effector system are involved in the mediation of effect. A brief review is given of the historical development of the adrenoceptor concept, of the classification of adrenoceptors, and of the consequences of stimulation and blockade of these receptors by drugs.
药物与受体之间的相互作用引发一系列反应,导致生理反应。效应的介导涉及一个识别位点、一个放大系统和一个效应器系统。本文简要回顾了肾上腺素能受体概念的历史发展、肾上腺素能受体的分类,以及药物对这些受体的激动和阻断所产生的后果。