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马来酸氮卓斯汀/硫酸伪麻黄碱复方缓释片与安慰剂治疗重度常年性变应性鼻炎的对比研究

Azatadine maleate/pseudoephedrine sulfate repetabs versus placebo in the treatment of severe perennial allergic rhinitis.

作者信息

Zubizaretta J

出版信息

J Int Med Res. 1980;8(6):395-9. doi: 10.1177/030006058000800605.

Abstract

Sixty patients took part in a randomized double-blind comparison of azatadine/pseudoephedrine versus placebo for the treatment of severe perennial allergic rhinitis. After 2 weeks of therapy subjective patient appraisal as well as objective physician evaluation showed the active drug combination to have a beneficial effect (72% good to excellent improvement versus 40% for placebo) in reducing the signs and symptoms of this allergic disorder. No adverse reactions were reported.

摘要

60名患者参与了氮卓斯汀/伪麻黄碱与安慰剂治疗重度常年性变应性鼻炎的随机双盲对照试验。治疗2周后,患者主观评估以及医生客观评价显示,活性药物组合在减轻该变应性疾病的体征和症状方面具有有益效果(72%改善良好至极佳,而安慰剂组为40%)。未报告不良反应。

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