Lossnitzer K, Gäb J
Fortschr Med. 1980 Aug 7;98(29):(1133-6).
In 7 patients suffering from orthostatic hypotension the early behaviour of arterial mean blood pressure was studied in the tilting table experiment under influence of etilefrine, norfenefrine, gepefrine (D-(+)-1-(3-hydroxyphenyl)-2-aminopropan-(2R, 3R)-hydrogentartrat) and of its I-isomere. Significant improvement of early orthostatic disregulation of the arterial pressure could be only observed under gepefrine. Amelioration seems to be induced by sensitization of the pressoreceptors.
在7例体位性低血压患者中,于倾斜试验台上研究了依托利明、去甲麻黄碱、吉培福明(D-(+)-1-(3-羟苯基)-2-氨基丙烷-(2R, 3R)-酒石酸氢盐)及其I-异构体对动脉平均血压早期变化的影响。仅在吉培福明作用下可观察到动脉压早期体位性调节障碍有显著改善。这种改善似乎是由压力感受器的敏感性增强所致。