Wambach G, Finke K, Saborowski F
Med Klin. 1980 Dec 19;75(26):917-20.
The clinical picture of the panarteritis nodosa is characterized by vague early symptoms, manifestations in various organs and a changing prognosis. In seven patients with histologically proven panarteritis nodosa the clinical course was followed up over a long period. The commonest early symptoms were fever of unknown origin and a considerable loss of weight. Three out of seven patients showed in the initial phase a hypertension, in two other patients the blood pressure rose as the disease progressed. Those patients, whose renal function was impaired when the diagnosis was established, had a poor prognosis in spite of immunosuppressive therapy and dialysis. The life expectancy of these patients was between two and 16 months (in average 6,4 months). On the other side the clinical course in two patients without renal failure was more favourable; they are alive eight months and 15 years respectively after the diagnosis was confirmed.
结节性多动脉炎的临床表现特点为早期症状不明确、累及多个器官以及预后多变。对7例经组织学证实为结节性多动脉炎的患者进行了长期临床病程随访。最常见的早期症状是不明原因发热和体重显著减轻。7例患者中有3例在疾病初期出现高血压，另外2例患者血压随病情进展而升高。那些在确诊时肾功能就已受损的患者，尽管接受了免疫抑制治疗和透析，预后仍较差。这些患者的预期寿命在2至16个月之间（平均6.4个月）。另一方面，2例无肾衰竭患者的临床病程则较为良好；确诊后分别存活了8个月和15年。
