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通过服用吡拉西坦观察老年人适应行为的变化(作者译)

[Changes in the adaptation behavior in old age through piracetam intake (author's transl)].

作者信息

Pusch H J, Schmitz-Dräger B

出版信息

Aktuelle Gerontol. 1980 Oct;10(10):457-62.

PMID:6110352
Abstract

The primary goal of all regulatory processes is to preserve the internal steady state. We summarize the elapsing mechanisms with the definition "adaptation". Statements about that without considering the vigilance are impossible. Adaptation and vigilance are closely related to each other. If the verified "Pirazetam" (Normabrain) influences the vigilance, it should be possible to proof changes in the adaptation, which according to hormonal results in insulin hypoglycemia might be registered. The behavior of cortisol ahd STH are the same before and after medication, however a significant higher noradrenalin secretion can be traced after treatment. This effect is rated as a positive influence of the medication on the suprarenal medulla, which on the contrary is regarded as a prolonged part of the brain.

摘要

所有调节过程的主要目标是维持内稳态。我们用“适应”这一定义来概括其过程机制。若不考虑警觉性,就无法对其进行阐述。适应与警觉性彼此密切相关。如果经证实的“吡拉西坦”(脑复康)会影响警觉性,那么就应该能够证明适应过程中的变化,根据激素导致胰岛素低血糖的结果或许可以检测到这些变化。用药前后皮质醇和生长激素的行为并无差异,然而治疗后可发现去甲肾上腺素分泌显著增加。这种效应被认为是药物对肾上腺髓质产生的积极影响,而肾上腺髓质反过来又被视为大脑的延伸部分。

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