Hama K
J Neurocytol. 1980 Dec;9(6):845-60. doi: 10.1007/BF01205023.
Membrane specializations at the active zone of the afferent synapse in the saccular macula of goldfish are described. Those of the presynaptic membrane consist of three to six elongated aggregates of intramembrane particles separated by particle-free furrows on the concave part of the P face and its complementary figure, that is, an alternate arrangement of elongated aggregates of pits and smooth ridges on the convex part of the E face. The size of the specialized area is about 0.5 micrometer x 0.3 micrometer. Vesicle fusion sites are situated at the margin of the particle-free furrow and ridge of the presynaptic active zone. Round pores about 30-50 nm in diameter are seen on the P face around the active zone. They are probably openings of the anastomosing tubules or coated pits. A focal aggregate of intramembrane particles is observed on the E face of the postsynaptic membrane apposing the presynaptic active zone. The P face of the postsynaptic active zone shows pits and particles. Small gap junctions are found between hair cells and adjacent supporting cells. They are frequently associated with desmosomes. The possible functional significance of these gap junctions is discussed.
描述了金鱼球囊斑传入突触活性区的膜特化结构。突触前膜的膜特化结构由三到六个膜内颗粒的细长聚集体组成，在P面凹面及其互补面由无颗粒沟隔开，即在E面凸面由凹坑和光滑嵴的细长聚集体交替排列。特化区域的大小约为0.5微米×0.3微米。囊泡融合位点位于突触前活性区无颗粒沟和嵴的边缘。在活性区周围的P面上可见直径约30 - 50纳米的圆形孔。它们可能是吻合小管或有被小窝的开口。在与突触前活性区相对的突触后膜E面上观察到膜内颗粒的局灶性聚集体。突触后活性区的P面显示有凹坑和颗粒。在毛细胞和相邻支持细胞之间发现了小的间隙连接。它们常与桥粒相关。讨论了这些间隙连接可能的功能意义。
