Schranz D, Stopfkuchen H, Jüngst B K
Monatsschr Kinderheilkd. 1981 Apr;129(4):248-50.
A 12 year boy with an isolated head injury and subdural hematoma developed neurogenic pulmonary edema and intraoperatively a low cardiac output syndrome. The postoperatively depressed cardiac function and hemorrhagic pulmonary edema were treated with Dobutamine and Nitroglycerin given intravenously. The beta-1-stimulating catecholamine was used because of its positive inotropic effect, to reduce pulmonary capillary pressure and to improve the afterload. Nitroglycerin applied in a low dosage with exclusive venodilator effect was added for treatment of pulmonary edema and left ventricular failure. About 2 1/2 h after the start of the treatment pulmonary edema had subsided and circulation was stabilized.
一名12岁男孩因单纯头部损伤和硬膜下血肿,出现神经源性肺水肿,并在术中出现低心排血量综合征。术后心脏功能抑制和出血性肺水肿通过静脉给予多巴酚丁胺和硝酸甘油进行治疗。使用β-1刺激儿茶酚胺是因其正性肌力作用,以降低肺毛细血管压力并改善后负荷。加入低剂量应用且具有单纯静脉扩张作用的硝酸甘油,用于治疗肺水肿和左心室衰竭。治疗开始约2个半小时后,肺水肿消退,循环稳定。