Goldring J R, McNaught W, Gillespie G
Aktuelle Probl Chir Orthop. 1981;19:101-4.
A combination of kanamycin and metronidazole administered for 3 days by mouth preoperatively, significantly suppresses both the aerobic and anaerobic colonic microflora, and significantly reduces the incidence of postoperative wound infection. During 6 years experience with this regimen, no toxic or untoward effects have been observed.
术前口服卡那霉素和甲硝唑联合用药3天,可显著抑制结肠需氧和厌氧微生物菌群,并显著降低术后伤口感染的发生率。在采用该方案的6年经验中,未观察到有毒或不良影响。