Dorn A, Bernstein H G, Hahn H J, Kostmann G, Ziegler M
Z Mikrosk Anat Forsch. 1981;95(3):381-4.
The content and the distribution of insulin, glucagon and somatostatin were studied in normoglycemic and hyperglycemic rodents by immunohistochemical techniques. A manifest Diabetes mellitus caused a striking decrease in somatostatin immunofluorescence. The insulin content suffered in a less pronounced manner. Data obtained with glucagon did not permit to draw unequivocal conclusions. In general, our findings speak about certain regulatory influence of the brain on glucose homeostasis.
通过免疫组织化学技术研究了正常血糖和高血糖啮齿动物体内胰岛素、胰高血糖素和生长抑素的含量及分布。明显的糖尿病导致生长抑素免疫荧光显著降低。胰岛素含量的降低则不太明显。关于胰高血糖素的数据无法得出明确结论。总体而言，我们的研究结果表明大脑对葡萄糖稳态具有一定的调节作用。
