[Immunohistochemical evidence of some peptidohormones in the central nervous system of normoglycemic and hyperglycemic rodents (author's transl)].

The content and the distribution of insulin, glucagon and somatostatin were studied in normoglycemic and hyperglycemic rodents by immunohistochemical techniques. A manifest Diabetes mellitus caused a striking decrease in somatostatin immunofluorescence. The insulin content suffered in a less pronounced manner. Data obtained with glucagon did not permit to draw unequivocal conclusions. In general, our findings speak about certain regulatory influence of the brain on glucose homeostasis.