Mathieu D, Mathieu A
Ann Anesthesiol Fr. 1981;22(3):305-8.
Anesthetic drugs have multiple effects on cellular structures and functions. Among these are membrane perturbations, cell division, DNA synthesis, disruption of microtubules and microfilaments, phagocytosis and cell locomotion. Some of these effects are reversible, and directly correlated to concentration and length of exposure; other, however, seriously compromise cellular integrity and vital functions. A review of the literature and current work are presented.
麻醉药物对细胞结构和功能有多种影响。其中包括膜扰动、细胞分裂、DNA合成、微管和微丝的破坏、吞噬作用和细胞运动。这些影响中的一些是可逆的,并且与浓度和暴露时间直接相关;然而,其他一些影响会严重损害细胞完整性和重要功能。本文对相关文献和当前研究工作进行了综述。