甲型流感病毒A/列宁格勒/134/57冷适应病毒株ts突变分析
Analysis of ts mutations of cold-adapted influenza A/Leningrad/134/57 virus variants.
作者信息
Lisovskaya K V, Garmashova L M, Medvedeva T E
出版信息
Acta Virol. 1981 Nov;25(6):415-7.
PMID:6120645
Abstract
By recombination of ts mutants of fowl plague virus belonging to different complementation groups with two cold-adapted variants of human influenza virus, the number and gene localization of ts mutations occurring in these variants was determined. In the course of passaging of human influenza virus at lowered temperature, the number of genes with ts mutations increased.
摘要
通过将属于不同互补群的禽痘病毒温度敏感（ts）突变体与两种人类流感病毒的冷适应变体进行重组，确定了这些变体中发生的ts突变的数量和基因定位。在低温传代人类流感病毒的过程中，带有ts突变的基因数量增加。
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