Goetz C G, Klawans H L
J Clin Psychopharmacol. 1981 Sep;1(5):297-303. doi: 10.1097/00004714-198109000-00005.
In psychiatric literature, the term extrapyramidal syndrome has traditionally encompassed a wide variety of drug-induced movement disorders. Recently, it has become increasingly clear that the natural history, pathophysiology, and pharmacology of individual movement disorders are distinct, making this unifying term obsolete and, in fact, a source of confusion. The topic of drug-induced movement disorders is reviewed, and a classification system based on anatomy, pharmacology, and therapeutic considerations is discussed.
在精神病学文献中,锥体外系综合征一词传统上涵盖了多种药物引起的运动障碍。最近,越来越清楚的是,个体运动障碍的自然病史、病理生理学和药理学是不同的,这使得这个统一的术语过时了,实际上还造成了混淆。本文对药物引起的运动障碍这一主题进行了综述,并讨论了一种基于解剖学、药理学和治疗考虑的分类系统。