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[金黄色苔藓或紫癜性苔藓;约5例;超微结构研究]

[Lichen aureus or lichen purpuricus; about 5 cases; ultrastructural study].

作者信息

Schnitzler L, Verret J L, Schubert B, Belaïch Belperron P

出版信息

Ann Dermatol Venereol. 1977 Nov;104(11):731-6.

PMID:612255
Abstract

Clinical, histological and ultrastructural features in five cases of lichen aureus are descirbed. This rare condition with ages ranging here from 6 to 31 consists of a pigmented papular and purpuric eruption. Unilaterally, trunk or limb may be involved, in a possible systematized distribution. The microscopic picture is characterized by a dense histiocytic and lymphocytic infiltration in the upper part of the dermis; extravasation of erythrocytes and iron pigment in the histiocytes are often noticed. In fine structure most cells of the dermal infiltrate are histiocytes (or macrophages) with numerous worm-like structures and even typical Langerhans granules in three cases; histiocytic cells; histiocytes are frequently seen in apposition to lymphocytes. In all these cases, no sign of histiocytosis X is found. Classification of lichen aureus in the group of idiopathic pigmented purpuric eruption is proposed.

摘要

本文描述了5例金黄色苔藓的临床、组织学和超微结构特征。这种罕见疾病的患者年龄在6岁至31岁之间,表现为色素沉着性丘疹和紫癜性皮疹。皮疹可单侧累及躯干或四肢,呈可能的系统性分布。显微镜下表现为真皮上部密集的组织细胞和淋巴细胞浸润;常可见红细胞外渗和组织细胞内的铁血黄素。在超微结构中,真皮浸润的大多数细胞是组织细胞(或巨噬细胞),其中3例有许多蠕虫样结构甚至典型的朗格汉斯颗粒;组织细胞;组织细胞常与淋巴细胞并列。在所有这些病例中,均未发现组织细胞增多症X的迹象。本文提出将金黄色苔藓归类于特发性色素性紫癜性皮疹组。

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