Sundqvist G, Johansson E
Scand J Dent Res. 1982 Feb;90(1):29-36. doi: 10.1111/j.1600-0722.1982.tb01521.x.
Bacteria belonging to the species B. melaninogenicus ss. melaninogenicus (two strains), B. melaninogenicus ss. intermedius (five strains), B. asaccharolyticus (seven strains), and Actinobacillus actinomycetemcomitans (four strains) were tested under anaerobic conditions for their sensitivity to the bactericidal effect of pooled human serum. The A. actinomycetemcomitans strains were not killed to any extent by the serum. Both B. melaninogenicus ss. melaninogenicus strains were killed by serum. The sensitivity to serum among the strains of B. asaccharolyticus and B. melaninogenicus ss. intermedius was diverse. There was no correlation between the sensitivity to serum among the strains and the levels of specific antibodies in the serum. The bactericidal activity of serum was only effective if the complement system was present in serum. All strains initiated activation of complement and binding of a C3 component to the cell surface both in normal and MgEGTA chelated serum. The possible role of serum bactericidal activity in the pathogenesis of oral infections is unclear.
对属于产黑色素类杆菌产黑色素亚种（2株）、产黑色素类杆菌中间亚种（5株）、不解糖卟啉单胞菌（7株）和伴放线放线杆菌（4株）的细菌，在厌氧条件下测试了它们对混合人血清杀菌作用的敏感性。伴放线放线杆菌菌株未被血清任何程度地杀灭。两株产黑色素类杆菌产黑色素亚种菌株被血清杀灭。不解糖卟啉单胞菌和产黑色素类杆菌中间亚种菌株对血清的敏感性各异。菌株对血清的敏感性与血清中特异性抗体水平之间无相关性。血清的杀菌活性仅在血清中存在补体系统时才有效。在正常血清和MgEGTA螯合血清中，所有菌株均引发补体激活及C3成分与细胞表面的结合。血清杀菌活性在口腔感染发病机制中的可能作用尚不清楚。
