牛弧菌病疫苗接种：单一生物型赋予的免疫力。

Bovine vibriosis vaccination: immunity conferred by a single biotype.

作者信息

Johns D R, Mater R J, Medveczky N E

出版信息

Aust Vet J. 1977 Oct;53(10):467-9. doi: 10.1111/j.1751-0813.1977.tb05461.x.

DOI:10.1111/j.1751-0813.1977.tb05461.x

Abstract

An adjuvant vaccine was prepared from an Australian isolate of Campy-lobacter fetus subsp fetus biotype intermedius and injected into 23 virgin Guernsey heifers. Ten nonvaccinated animals served as controls. When challenged by the intravaginal route with a culture of either the homologous strain or biotype venerealis, weekly swabs from the anterior vagina continued to yield either biotype in 8 of 10 nonvaccinates at 6 weeks as compared with 3 of 23 vaccinates. Serology in vaccinated heifers and rabbits showed that the vaccine produced high titres of antibody against both homologous and heterologous strains.

摘要

一种佐剂疫苗是由一株澳大利亚胎儿弯曲杆菌亚种胎儿中间生物型分离株制备而成，并注射到23头未产的根西岛小母牛体内。10头未接种疫苗的动物作为对照。当通过阴道内途径用同源菌株或性病生物型培养物进行攻毒时，与23头接种疫苗的动物中的3头相比，在6周时，10头未接种疫苗的动物中有8头阴道前部每周拭子检测仍能检出任一生物型。接种疫苗的小母牛和兔子的血清学检测表明，该疫苗产生了针对同源和异源菌株的高滴度抗体。