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用L-(13N)谷氨酸进行扫描:评估一名胚胎性横纹肌肉瘤患者对化疗的反应。

Scanning with L-(13 N) glutamate: Assessment of the response to chemotherapy of a patient with embryonal rhabdomyosarcoma.

作者信息

Sordillo P P, Reiman R E, Gelbard A S, Benua R S, Magill G B, Laughlin J S

出版信息

Am J Clin Oncol. 1982 Jun;5(3):285-9.

PMID:6123255
Abstract

The use of (13) N-labeled L-glutamate as an imaging agent in a patient with embryonal rhabdomyosarcoma is described. Localization of (13)N in a large, poorly defined tumor of the left pectoral region was seen, and clinically occult right axilliary metastases were also detected. A marked reduction in uptake in these areas occurred after chemotherapy, paralleling the clinical disappearance of tumor. These changes were verified on gallium scan. (13)N-labeled glutamate may be useful as an imaging agent, especially in patients with soft-tissue sarcomas.

摘要

本文描述了将(13)N标记的L-谷氨酸作为显像剂用于一名胚胎性横纹肌肉瘤患者的情况。在左胸区域一个边界不清的大肿瘤中可见(13)N的定位,同时也检测到了临床上隐匿的右腋窝转移灶。化疗后这些区域的摄取明显减少,与肿瘤的临床消失情况相符。镓扫描证实了这些变化。(13)N标记的谷氨酸可能作为一种显像剂有用,特别是在软组织肉瘤患者中。

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