Kostiunina Z G, Eletskiĭ V Iu
Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(4):117-20.
The use of the drug grandaxin (made in Hungary) has demonstrated its high activity in the treatment of psychopathological disturbances of neurotic origin. Its administration is preferable when vegetative and hyposthenic disturbances are prevalent in the neurosis clinical picture. At the same time it alleviates the intensity of phobic and senestho-hypochondriacal experiences, however, its administration as the sole means for eliminating these disturbances seems undesirable. Neither can grandaxin be the drug of choice in controlling anxious and agrypnic disturbances. Psychogenic somatic syndromes have also appeared to be insensitive to the treatment with this drug. The side-effects produced by grandaxin are mild. The most persistent are nausea and headaches which develop in patients receiving high doses and subside in most cases spontaneously on reduction of the latter. No complications were noted.
使用匈牙利生产的药物格兰达新已证明其在治疗神经症性精神病理障碍方面具有高活性。当神经症临床表现中以植物神经紊乱和体力衰弱为主时,使用该药较为适宜。同时,它可减轻恐惧及疑病性体验的强度,然而,将其作为消除这些障碍的唯一手段似乎并不理想。格兰达新也不是控制焦虑和失眠障碍的首选药物。心因性躯体综合征似乎对该药治疗也不敏感。格兰达新产生的副作用较轻。最常见的是恶心和头痛,在接受高剂量治疗的患者中出现,大多数情况下在减少剂量后会自行缓解。未发现并发症。