鸡内耳分离前庭组织中的γ-氨基丁酸合成
GABA synthesis in isolated vestibulary tissue of chick inner ear.
作者信息
Meza G, Carabez A, Ruíz M
出版信息
Brain Res. 1982 Jun 3;241(1):157-61. doi: 10.1016/0006-8993(82)91238-0.
PMID:6125239
Abstract
This study was undertaken to assess the possible participation of GABA in neurotransmission in the inner ear of higher vertebrates utilizing isolated chick vestibulary cristae as a model. GABA synthesis was investigated as a suitable criterion for postulating this amino acid as a putative neurotransmitter. Enzyme-mediated GABA synthesis was demonstrated implying a possible neurotransmitter role of this amino acid in the chick vestibule.
摘要
本研究旨在利用分离的鸡前庭嵴作为模型，评估γ-氨基丁酸（GABA）在高等脊椎动物内耳神经传递中可能的参与情况。研究了GABA的合成，以此作为假定这种氨基酸为一种潜在神经递质的合适标准。结果表明存在酶介导的GABA合成，这意味着该氨基酸在鸡前庭中可能具有神经递质的作用。
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