光诱发的雏鸡视叶GABA系统变化。
Light-evoked changes in chick optic lobe GABA system.
作者信息
Nisticò G, Ientile R, Rotiroti D, Di Giorgio R M
出版信息
Res Commun Chem Pathol Pharmacol. 1979 Jun;24(3):447-56.
PMID:451334
Abstract
In young chicks the effects of 3 min stroboscope stimulation on GABA and free glutamic acid content and on GAD and GABA-T activity in optic lobes were studied. A significant depletion in GABA and glutamic acid levels was found to occur. In addition a sustained increase in GABA-T and GAD activity was observed. In conclusion present experiments are in favour of an inhibitory role played by GABA in chick optic tectum during stroboscope stimulation.
摘要
在幼雏中，研究了3分钟频闪刺激对视叶中γ-氨基丁酸（GABA）和游离谷氨酸含量以及谷氨酸脱羧酶（GAD）和γ-氨基丁酸转氨酶（GABA-T）活性的影响。发现GABA和谷氨酸水平出现显著降低。此外，还观察到GABA-T和GAD活性持续增加。总之，目前的实验支持GABA在频闪刺激期间对雏鸡视顶盖发挥抑制作用。
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