Khanna N K, Hurkat P C, Theti T S
Indian J Physiol Pharmacol. 1977 Jul-Sep;21(3):180-5.
The acetylcholine level of dog heart has been determined under hypothermia. It was increased at 28 degrees C, and decrease at 20 degrees C. Further, it was observed that the heart rate and blood pressure decreased with gradual reduction in the body temperature of the dog and ventricular fibrillation occurred in 50% of the animals at 20 degrees C. It is proposed that cholinergic agents may have a role as antifibrillatory agents in hypothermia.
已在低温状态下测定了犬心脏的乙酰胆碱水平。在28摄氏度时其水平升高，而在20摄氏度时降低。此外，观察到随着犬体温逐渐降低，心率和血压下降，并且在20摄氏度时50%的动物发生了心室颤动。有人提出，胆碱能药物在低温状态下可能具有抗纤颤药物的作用。
