Calcium channel blocking drugs for chronic, stable angina. Verapamil.

Verapamil is effective primary therapy for angina pectoris at a dosage of about 120 mg three times a day. In equal doses it has the same antianginal effect as propranolol although the mechanism of action is different. Long-term therapy is effective and well tolerated. Side effects are few and if required, verapamil may be given with nitrates or beta-blockers.