Svensson G
Rhinology. 1982 Sep;20(3):159-66.
During 4 weeks of the grass pollen season in the south of Sweden 27 patients with seasonal allergic rhinitis were treated topically with a beta-adrenoceptor stimulant, KWD 2131, which in an earlier rhinomanometric study had shown a prophylactic effect at nasal allergen provocations in hay-fever patients. A clinical effect of KWD 2131 could not be documented in this randomized placebo-controlled, double-blind comparative study. The results contribute to conclusions in the clinical implications of rhinomanometric data.
在瑞典南部草花粉季节的4周时间里，27名季节性变应性鼻炎患者局部使用了一种β-肾上腺素能受体兴奋剂KWD 2131进行治疗。在之前的一项鼻阻力测量研究中，该药物在花粉热患者的鼻腔过敏原激发试验中显示出预防作用。在这项随机、安慰剂对照、双盲比较研究中，未记录到KWD 2131的临床疗效。这些结果有助于得出鼻阻力测量数据临床意义的结论。
