大鼠杏仁核或皮层对三叉神经运动神经元逆向活动的易化作用。

Amygdaloid or cortical facilitation of antidromic activity of trigeminal motoneurons in the rat.

Mishima K, Sasamoto K, Ohta M

Comp Biochem Physiol A Comp Physiol. 1982;73(3):355-9. doi: 10.1016/0300-9629(82)90167-0.

Abstract

Electrical stimulation of the rat's contralateral central amygdaloid (CAm) nucleus or the contralateral frontal cortex markedly augmented the antidromic field potential evoked by stimulation of mylohyoid (Myl) nerve. 2. This facilitation was shown to be due to EPSPs of the mylohyoid-anterior digastric (Myl-Dig) motoneurons. 3. In a few motoneurons, cortical EPSPs had fixed short latencies following high-frequency double stimuli and this is believed to be due to a monosynaptic pathway. 4. The amygdaloid or cortically evoked EPSPs relieved IS-SD blockade in a few motoneurons and also facilitated antidromic discharge in others which did not show any IS or M spike response to the same subthreshold antidromic stimulation. The underlying mechanisms are discussed.

摘要

对大鼠对侧中央杏仁核（CAm）核或对侧额叶皮质进行电刺激，可显著增强刺激下颌舌骨肌（Myl）神经所诱发的逆向场电位。2. 这种易化作用被证明是由于下颌舌骨肌 - 二腹肌前腹（Myl - Dig）运动神经元的兴奋性突触后电位（EPSP）所致。3. 在少数运动神经元中，高频双刺激后皮质EPSP具有固定的短潜伏期，这被认为是由于单突触通路所致。4. 杏仁核或皮质诱发的EPSP在少数运动神经元中解除了IS - SD阻断，并且在其他对相同阈下逆向刺激未表现出任何IS或M峰反应的运动神经元中也促进了逆向放电。文中讨论了其潜在机制。