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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Tempel G E, Parks L H

Comp Biochem Physiol C Comp Pharmacol. 1982;73(2):377-81. doi: 10.1016/0306-4492(82)90138-1.

Norepinephrine (NE) and serotonin (5-HT) were simultaneously assessed in 4 discrete regions of the brain of the golden hamster. 2. Hypothalamic concentrations of both these amines are reported for the following groups: (1) normothermic controls; (2) heat acclimated; (3) cold acclimated; (4) helium-cold hypothermic; (5) rewarming; and (6) rewarmed. 3. Heat acclimated animals demonstrated approximately 35 and 25% decreases from control values for NE and 5-HT, respectively. Cold acclimated hamsters were not significantly different from controls. Helium-cold hypothermia resulted in approximately a 30 and 20% decrease in NE and 5-HT, respectively, with the latter returning to control values during rewarming. 4. The data provide indirect evidence for the involvement of NE in central pathways involving heat gain and 5-HT in pathways involving heat loss, and are discussed in terms of FELBERG & MYER'S (1964 J. Physiol., Lond. 173. 226-236) bioamine theory of thermoregulation.

在金黄地鼠大脑的4个不同区域同时评估了去甲肾上腺素（NE）和5-羟色胺（5-HT）。2. 报告了以下几组动物下丘脑这些胺类的浓度：（1）体温正常的对照组；（2）热适应组；（3）冷适应组；（4）氦冷低温组；（5）复温组；（6）复温后组。3. 热适应动物的NE和5-HT浓度分别比对照值降低了约35%和25%。冷适应地鼠与对照组无显著差异。氦冷低温导致NE和5-HT分别降低约30%和20%，后者在复温过程中恢复到对照值。4. 这些数据为NE参与涉及产热的中枢途径以及5-HT参与涉及散热的途径提供了间接证据，并根据费尔贝格和迈耶（1964年，《伦敦生理学杂志》，第173卷，226 - 236页）的生物胺体温调节理论进行了讨论。

Tempel G E, Parks L H

Comp Biochem Physiol C Comp Pharmacol. 1982;73(2):377-81. doi: 10.1016/0306-4492(82)90138-1.

Norepinephrine (NE) and serotonin (5-HT) were simultaneously assessed in 4 discrete regions of the brain of the golden hamster. 2. Hypothalamic concentrations of both these amines are reported for the following groups: (1) normothermic controls; (2) heat acclimated; (3) cold acclimated; (4) helium-cold hypothermic; (5) rewarming; and (6) rewarmed. 3. Heat acclimated animals demonstrated approximately 35 and 25% decreases from control values for NE and 5-HT, respectively. Cold acclimated hamsters were not significantly different from controls. Helium-cold hypothermia resulted in approximately a 30 and 20% decrease in NE and 5-HT, respectively, with the latter returning to control values during rewarming. 4. The data provide indirect evidence for the involvement of NE in central pathways involving heat gain and 5-HT in pathways involving heat loss, and are discussed in terms of FELBERG & MYER'S (1964 J. Physiol., Lond. 173. 226-236) bioamine theory of thermoregulation.

在金黄地鼠大脑的4个不同区域同时评估了去甲肾上腺素（NE）和5-羟色胺（5-HT）。2. 报告了以下几组动物下丘脑这些胺类的浓度：（1）体温正常的对照组；（2）热适应组；（3）冷适应组；（4）氦冷低温组；（5）复温组；（6）复温后组。3. 热适应动物的NE和5-HT浓度分别比对照值降低了约35%和25%。冷适应地鼠与对照组无显著差异。氦冷低温导致NE和5-HT分别降低约30%和20%，后者在复温过程中恢复到对照值。4. 这些数据为NE参与涉及产热的中枢途径以及5-HT参与涉及散热的途径提供了间接证据，并根据费尔贝格和迈耶（1964年，《伦敦生理学杂志》，第173卷，226 - 236页）的生物胺体温调节理论进行了讨论。