Hanumante M M, Fingerman M
Life Sci. 1982 Dec 13;31(24):2667-72. doi: 10.1016/0024-3205(82)90710-x.
This article reviews the endocrinological, pharmacological and biochemical evidence ascribing neurotransmitter roles for 5-hydroxytryptamine (5-HT, serotonin) in eliciting the release of red pigment-dispersing hormone (RPDH) and for dopamine (DA) in stimulating the release of red pigment-concentrating hormone (RPCH) in the fiddler crab, Uca pugilator. 5-HT produces red pigment dispersion in intact crabs, but only indirectly. Likewise, DA evokes red pigment concentration in vivo but it has no effect on red chromatophores (erythrophores) in isolated legs. The data obtained with 5-HT and DA agonists and antagonists on red pigment translocation in vivo and in vitro, are consistent with their neurotransmitter candidacies in evoking the release of these erythrophorotropic hormones.
本文综述了内分泌学、药理学和生物化学方面的证据,这些证据表明5-羟色胺(5-HT,血清素)在招潮蟹Uca pugilator中引发红色素分散激素(RPDH)释放时具有神经递质作用,以及多巴胺(DA)在刺激红色素浓缩激素(RPCH)释放时具有神经递质作用。5-HT在完整的螃蟹中会产生红色素分散,但只是间接作用。同样,DA在体内会引起红色素浓缩,但对离体蟹腿中的红色色素细胞(红色素细胞)没有影响。使用5-HT和DA激动剂及拮抗剂在体内和体外对红色素转运所获得的数据,与它们作为神经递质引发这些促红色素细胞激素释放的候选作用相一致。