原发性情感障碍的当前心理药物遗传学策略
Current psychopharmacogenetic strategies in primary affective disorders.
作者信息
Waters B G, Lapierre Y D
出版信息
Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(4-6):675-9. doi: 10.1016/s0278-5846(82)80168-1.
PMID:6131496
Abstract
- The evidence is substantial that primary affective disorders are genetically inherited. 2. Using pharmacological probes or strategies, biological markers of the gene(s) should be able to be ascertained or induced during remission of illness. 3. Genetic marker criteria are defined and are applied to the scanty existing data. 4. It is concluded that these strategies have yet to yield a clear marker of primary affective disorder.
摘要
- 有充分证据表明原发性情感障碍是遗传的。2. 利用药理学探针或策略，应该能够在疾病缓解期确定或诱导出相关基因的生物学标志物。3. 定义了遗传标志物标准并将其应用于现有的少量数据。4. 得出的结论是，这些策略尚未产生原发性情感障碍的明确标志物。
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