Rizzo P A, Albani G F, Spadaro M, Morocutti C
Biol Psychiatry. 1983 Feb;18(2):175-83.
This is a study of possible CNV correlations to schizophrenia. Three groups of schizophrenic patients were examined: 14 patients with an initial acute psychotic illness, before and after neuroleptic therapy; 9 subjects with chronic schizophrenia, who did not require continuous neuroleptic therapy; 18 patients with chronic schizophrenia under almost continuous neuroleptic therapy for many years. The results were compared with CNV parameters of a control group. On the basis of the results obtained, the authors advance the view that the different modes of manifestation of cerebral bioelectric reactivity (CNV) are independent of treatment and are related to the different stages of the evolution of the disorder.
这是一项关于可能的拷贝数变异(CNV)与精神分裂症相关性的研究。研究对三组精神分裂症患者进行了检查:14例初发急性精神病性疾病患者,在接受抗精神病药物治疗前后;9例慢性精神分裂症患者,他们不需要持续的抗精神病药物治疗;18例多年来几乎持续接受抗精神病药物治疗的慢性精神分裂症患者。将结果与对照组的CNV参数进行了比较。基于所获得的结果,作者提出观点,即脑生物电反应性(CNV)的不同表现模式与治疗无关,而是与疾病演变的不同阶段相关。