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[α-和β-肾上腺素能受体、M-胆碱能受体及H1-组胺受体激活对蛙锁骨下静脉机械张力的影响]

[Effect of activation of alpha- and beta-adrenergic receptors, M-cholinergic receptors and H1-histamine receptors on mechanical tension in the frog subclavian vein].

作者信息

Protas L L, Sysoev V V, Leont'eva G R

出版信息

Biull Eksp Biol Med. 1983 Jan;95(1):58-60.

PMID:6131707
Abstract

The effects of adrenaline, noradrenaline, isoproterenol, dopamine, histamine, acetylcholine, and serotonin on the wall tension in the isolated frog subclavian vein and modification of these effects by appropriate antagonists were examined. The existence of alpha- and beta-adreno-, M-choline- and H1-histamine receptors was demonstrated. Stimulation of alpha-adreno- and H1-histamine receptors augments and that of beta-adreno- and M-cholinoreceptors diminishes active wall tension in the vein.

摘要

研究了肾上腺素、去甲肾上腺素、异丙肾上腺素、多巴胺、组胺、乙酰胆碱和5-羟色胺对离体青蛙锁骨下静脉壁张力的影响,以及相应拮抗剂对这些影响的改变。证实了α-和β-肾上腺素能、M-胆碱能和H1-组胺受体的存在。刺激α-肾上腺素能和H1-组胺受体会增加静脉的主动壁张力,而刺激β-肾上腺素能和M-胆碱受体会降低静脉的主动壁张力。

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