人类神经系统肿瘤的化疗：对脑脊液固醇的影响
Chemotherapy of human nervous system tumors: influence on cerebrospinal fluid sterols.
作者信息
Paoletti P, Pezzotta S, Racca A R, Fumagalli R
出版信息
Natl Cancer Inst Monogr. 1977 Dec;46:125-6.
PMID:613223
Abstract
The cerebrospinal fluid levels of cholesterol, desmosterol, and the ratio 100 D:C taken from a study of 59 patients are reported. The patients, who had tumors of the nervous system, underwent neurosurgery, radiotherapy, and chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea or 1-(2-chlororethyl)-3-cyclohexyl-1-nitrosourea. The relationships among the levels of these three parameters and the clinical and neuroradiologic evolution are discussed.
摘要
报告了一项对59名患者的研究中脑脊液中胆固醇、羊毛甾醇的水平以及100 D:C比率。这些患者患有神经系统肿瘤，接受了神经外科手术、放疗以及使用1,3 - 双（2 - 氯乙基）- 1 - 亚硝基脲或1 - （2 - 氯乙基）- 3 - 环己基 - 1 - 亚硝基脲进行的化疗。讨论了这三个参数水平与临床及神经放射学进展之间的关系。
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Chemotherapy of human nervous system tumors: influence on cerebrospinal fluid sterols.人类神经系统肿瘤的化疗：对脑脊液固醇的影响
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