9-(R,S)-(2,3-二羟基丙基)腺嘌呤对蜱传脑炎病毒作用的研究
Studies on the effect of 9-(R, S)-(2,3-dihydroxypropyl)adenine on tick-borne encephalitis virus.
作者信息
Gresíková M, Rada B, Holý A
出版信息
Acta Virol. 1982 Dec;26(6):521-3.
PMID:6132547
Abstract
Peroral treatment with 9-(R, S)-(2,3-dihydroxypropyl) adenine did not protect mice infected with tick-borne encephalitis (TBE) viruses (strains Hypr and Ir13) when the drug was administered at the time or infection and/or up to day 2 after infection. The analogue inhibited the haemagglutination activity of the Skalica strain in vitro.
摘要
当在感染时和/或感染后2天内给予9-(R,S)-(2,3-二羟基丙基)腺嘌呤进行口服治疗时，并未保护感染蜱传脑炎（TBE）病毒（Hypr和Ir13株）的小鼠。该类似物在体外抑制了Skalica株的血凝活性。
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