Foster G A, Sanderson P J, Roberts P J
Eur J Pharmacol. 1983 Feb 18;87(2-3):253-8. doi: 10.1016/0014-2999(83)90335-7.
Noradrenaline produced a stereospecific and dose-related stimulation of cyclic GMP levels in incubated mouse cerebellar slices. The effect was mimicked by beta-agonists such as isoprenaline while the alpha-agonist phenylephrine was only weakly active. Experiments with selective beta 1- and beta 2-adrenoceptor agonists and antagonists, indicated that beta 2-receptors are the dominant class involved in the cyclic GMP response.
去甲肾上腺素对培养的小鼠小脑切片中环状鸟苷酸（cGMP）水平产生了立体特异性和剂量相关的刺激作用。β-激动剂如异丙肾上腺素可模拟该效应，而α-激动剂去氧肾上腺素的活性则很弱。使用选择性β1和β2肾上腺素能受体激动剂及拮抗剂进行的实验表明，β2受体是参与cGMP反应的主要类型。
