β-肾上腺素能受体阻断后冠状动脉血管阻力的自动调节
Autoregulation of the coronary vascular resistance after beta-adrenergic receptor blockade.
作者信息
Gattullo D, Losano G, Vacca G
出版信息
Boll Soc Ital Biol Sper. 1983 Jan 31;59(1):14-9.
It was previously observed that at the beginning of a 10 sec multiple arterial haemorrhage, vascular elasticity induces an increase of coronary vascular resistance, which in the late part of the haemorrhage is counteracted by the relaxation of the vascular smooth muscle fibres. In the present study the effect of multiple arterial haemorrhage on the coronary vascular resistance was studied after beta-adrenergic receptor blockade. The results suggest that also in these circumstances an elastic mechanism precedes a myogenic mechanism in the regulation of coronary vascular resistance.
先前观察到，在10秒多次动脉出血开始时，血管弹性会导致冠状动脉阻力增加，而在出血后期，这种增加会被血管平滑肌纤维的舒张所抵消。在本研究中，在β-肾上腺素能受体阻断后，研究了多次动脉出血对冠状动脉阻力的影响。结果表明，在这些情况下，在冠状动脉阻力调节中，弹性机制也先于肌源性机制。
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