Bruyland M, Verbruggen L, Maes E, Six R, Somers G, Ebinger G
Clin Neurol Neurosurg. 1983;85(1):49-55. doi: 10.1016/0303-8467(83)90023-9.
A case of MEN type IIa is described showing among other symptoms, three attacks of transient neurological symptoms. These were attributed to a localized, transient cerebral ischemia. The latter probably developed as a consequence of the concomitant occurrence of different phenomena: the existence of hypercalcemia and on the other hand the secretion of vasoactive substances by one of the three tumours forming the MEN type IIa syndrome. The pheochromocytoma played an essential role because the symptoms did not recur after the bilateral adrenalectomy.
本文描述了一例IIa型多发性内分泌腺瘤病(MEN),除其他症状外,患者出现了三次短暂性神经症状发作。这些症状归因于局限性短暂性脑缺血。后者可能是由于多种不同现象同时出现所致:高钙血症的存在,以及构成IIa型MEN综合征的三种肿瘤之一分泌血管活性物质。嗜铬细胞瘤起了关键作用,因为双侧肾上腺切除术后症状未再复发。