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大鼠纹状体中生长抑素和胆碱能神经元不同群体的组织化学证明。

Histochemical demonstration of separate populations of somatostatin and cholinergic neurons in the rat striatum.

作者信息

Vincent S R, Staines W A, Fibiger H C

出版信息

Neurosci Lett. 1983 Feb 21;35(2):111-4. doi: 10.1016/0304-3940(83)90536-0.

DOI:10.1016/0304-3940(83)90536-0
PMID:6134260
Abstract

Striatal neurons containing acetylcholine and somatostatin were examined using a pharmacohistochemical procedure for acetylcholinesterase and NADPH-diaphorase histochemistry respectively. The use of these two histochemical procedures allowed both cholinergic and somatostatin cells to be visualized simultaneously in single sections of the striatum. The results indicate that somatostatin and acetylcholine are contained in separate populations of striatal neurons and illustrate the utility of simple histochemical procedures to visualize biochemically defined neurons.

摘要

分别使用乙酰胆碱酯酶和NADPH - 黄递酶组织化学的药物组织化学方法检查含有乙酰胆碱和生长抑素的纹状体神经元。这两种组织化学方法的使用使得胆碱能细胞和生长抑素细胞能够在纹状体的单个切片中同时可视化。结果表明,生长抑素和乙酰胆碱存在于纹状体神经元的不同群体中,并说明了简单组织化学方法在可视化生化定义的神经元方面的实用性。

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