痛经时的月经量：丙氧苯宗和吲哚美辛的作用

Menstrual blood loss in dysmenorrhoea: effects of proquazone and indomethacin.

作者信息

Mäkäräinen L, Ylikorkala O

出版信息

Br J Obstet Gynaecol. 1983 Jun;90(6):570-2. doi: 10.1111/j.1471-0528.1983.tb08970.x.

DOI:10.1111/j.1471-0528.1983.tb08970.x

Abstract

Abnormal production of uterine prostaglandins (PG) causes primary dysmenorrhoea and excessive menstrual blood loss (MBL). We measured here MBL in primary dysmenorrhoea and found it to be normal during treatment with opiate analgesics (33.5 +/- 21.6 ml; mean +/- SD. n = 13), placebo (33.4 +/- 18.6 ml; n = 8), proquazone (31.8 +/- 18.0 ml; n = 8) and indomethacin (26.4 +/- 18.7 ml; n = 8). Proquazone and indomethacin relieved pain and other dysmenorrhoeic symptoms similarly in 33 women.

摘要

子宫前列腺素（PG）的异常产生会导致原发性痛经和月经过多（MBL）。我们在此测量了原发性痛经患者的MBL，发现其在使用阿片类镇痛药治疗期间正常（33.5±21.6毫升；平均值±标准差，n = 13），安慰剂（33.4±18.6毫升；n = 8），丙氧苯唑（31.8±18.0毫升；n = 8）和吲哚美辛（26.4±18.7毫升；n = 8）。丙氧苯唑和吲哚美辛在33名女性中缓解疼痛和其他痛经症状的效果相似。