β-肾上腺素能激动剂对大鼠肺中磷脂酶A2的体内抑制作用。
In vivo inhibition of phospholipase A2 in rat lung by an beta-adrenergic agonist.
作者信息
Wichert P V, Meyer W
出版信息
Agents Actions. 1983 Apr;13(2-3):233-4. doi: 10.1007/BF01967339.
PMID:6135325
Abstract
Phospholipase A2 is the key enzyme for the release of arachidonic acid derived mediators via cycloxygenase or lipoxygenase pathways in inflammation and immunological processes. Activity of microsomal phospholipase A2 in rat lung can be inhibited by in vivo application of the beta-adrenergic drug fenoterol both in control and diseased animals.
摘要
磷脂酶A2是在炎症和免疫过程中通过环氧化酶或脂氧合酶途径释放花生四烯酸衍生介质的关键酶。在对照动物和患病动物中，体内应用β-肾上腺素能药物非诺特罗均可抑制大鼠肺微粒体磷脂酶A2的活性。
Zotero 插件