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[痰细胞诊断作为肺癌检测筛查方法的价值——一项研究结果(作者译)]

[The value of sputum cytodiagnosis as a screening method for lung cancer detection--results of a study (author's transl)].

作者信息

Jäger J, Wilde J

出版信息

Z Erkr Atmungsorgane. 1977 Aug;149(3):307-12.

PMID:613545
Abstract

In the course of a screening program for lung cancer detection which has been going on for several years, 2432 male risk persons, aged 42-67, were examined cytologically in 1974 and 1975. The annual rate of incidence of lung cancer in this population is unknown. We estimate it at 3-4%. From two sputa of each patient we screened one specimen. 24.7% of the sputa were unsatisfactory. In the remaining preparations there were neither tumor cells nor cells suspicious for cancer. This result is discussed in view of the experiences of other authors, that the sensitivity of cytological screening for lung cancer is 33-38%. Recommendations are given for increasing the number of detected cases.

摘要

在一项持续数年的肺癌检测筛查项目过程中,1974年和1975年对2432名年龄在42至67岁的男性高危人群进行了细胞学检查。该人群中肺癌的年发病率未知。我们估计为3%至4%。从每位患者的两份痰液样本中筛选一份样本。24.7%的痰液样本不合格。在其余的样本中,既没有肿瘤细胞,也没有可疑癌细胞。结合其他作者的经验,即肺癌细胞学筛查的敏感性为33%至38%,对这一结果进行了讨论。并给出了增加检测病例数的建议。

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1
[The value of sputum cytodiagnosis as a screening method for lung cancer detection--results of a study (author's transl)].[痰细胞诊断作为肺癌检测筛查方法的价值——一项研究结果(作者译)]
Z Erkr Atmungsorgane. 1977 Aug;149(3):307-12.
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Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer.在肺癌高危个体的痰液细胞中,5号染色体短臂15区、6号染色体短臂11区至长臂11区、7号染色体短臂12区和8号染色体长臂24区的拷贝数增加情况较为罕见。
Lung Cancer. 2006 Nov;54(2):169-76. doi: 10.1016/j.lungcan.2006.07.009. Epub 2006 Aug 28.
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[Possibilities and limits of bronchial cancer detection by means of cytological examination of sputum].[通过痰液细胞学检查检测支气管癌的可能性与局限性]
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[New trends in the cytodiagnosis of bronchial carcinoma (author's transl)].支气管癌细胞诊断的新趋势(作者译)
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