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[通过促甲状腺激素释放激素和地塞米松试验对抑郁症进行生物学诊断]

[Biologic diagnosis of depression by the TRH and dexamethasone tests].

作者信息

Chabrol H, Moron P

出版信息

Encephale. 1983;9(1):1-22.

PMID:6135596
Abstract

Nowadays the diagnosis of depression can be made through two neuroendocrine tests, which tend to become common: the TRH test and the Dexamethasone Suppression Test which have a wide diagnostic accuracy. Any abnormal finding could implicate a dysfunction of neurotransmitter systems. They are of diagnostic assistance in endogenous depressions supposed to be responsive to antidepressants. They might also be a practical monitor of treatment response since the test results reverting to normal seems to indicate recovery whereas persisting abnormal results are a possible predictor of relapse.

摘要

如今,抑郁症的诊断可以通过两种逐渐变得常见的神经内分泌测试来进行:促甲状腺激素释放激素(TRH)测试和地塞米松抑制试验,它们具有广泛的诊断准确性。任何异常发现都可能意味着神经递质系统功能障碍。它们有助于诊断对抑郁症药物有反应的内源性抑郁症。它们也可能是治疗反应的实际监测指标,因为测试结果恢复正常似乎表明康复,而持续异常的结果可能是复发的预测指标。

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