Nguyen-Legros J, Vigny A, Gay M
Exp Eye Res. 1983 Jul;37(1):23-32. doi: 10.1016/0014-4835(83)90146-x.
The post-natal development of catecholaminergic neurons has been studied in the rat retina, using tyrosine-hydroxylase immunohistochemistry. The first TH-like immunoreactive cells were observed by the third post-natal day. The differentiation of neurons and the development of their processes continued until and after, the opening of the eyes (14-15th post-natal day). The catecholaminergic system was fully developed by three weeks of age. The use of retinal flat mounts treated with PAP-immunoperoxidase technique allowed a morphological observation of TH-like immunoreactive whole neurons.
利用酪氨酸羟化酶免疫组织化学方法，对大鼠视网膜中儿茶酚胺能神经元的产后发育进行了研究。在出生后第3天观察到首个TH样免疫反应性细胞。神经元的分化及其突起的发育一直持续到睁眼时（出生后第14 - 15天）及睁眼之后。儿茶酚胺能系统在3周龄时完全发育成熟。采用PAP免疫过氧化物酶技术处理视网膜平铺片，能够对TH样免疫反应性全神经元进行形态学观察。
